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Gas Exchange — A-Level Biology Revision

Revise Gas Exchange for A-Level Biology. Step-by-step explanation, worked examples, common mistakes and exam-style practice aligned to AQA, Edexcel and OCR.

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Gas Exchange in A-Level Biology: explanation, examples, and practice links on this page.
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Practice is aligned to major specifications (AQA, Edexcel, OCR, WJEC, Eduqas, Cambridge International (CIE), SQA, IB, AP).
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Curriculum index — BiologySubject overview

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Related topics in Exchange & Transport

  • Carbohydrates
  • Proteins

What is Gas Exchange?

Gas exchange is the physical process by which gases move passively by diffusion across a surface. In A-Level Biology, this focuses on the exchange of oxygen and carbon dioxide between an organism and its environment. Efficient gas exchange surfaces, such as the alveoli in the lungs or the gills in fish, share common features: a large surface area, a thin diffusion pathway, and a steep concentration gradient maintained by a good blood supply and ventilation.

Board notes: Gas exchange in humans, fish, and insects is a core topic for all A-Level Biology boards (AQA, Edexcel, OCR). The level of detail on lung volumes and the control of breathing may vary. AQA and OCR place a strong emphasis on the interpretation of spirometry data.

Step-by-step explanation

Worked example

To calculate the FEV1/FVC ratio, you use a spirometer. If a person has a Forced Vital Capacity (FVC) of 5.0 litres and a Forced Expiratory Volume in 1 second (FEV1) of 4.0 litres, the ratio is 4.0 / 5.0 = 0.8. A healthy ratio is typically around 0.7-0.8. A lower ratio can indicate an obstructive lung disease like asthma or COPD.

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Common mistakes

  • 1Confusing ventilation with gas exchange. Ventilation is the movement of the environmental medium (air or water) over the respiratory surface (e.g., breathing), which maintains the concentration gradient for diffusion, but it is not the diffusion process itself.
  • 2Forgetting the role of surfactant in the alveoli. Surfactant is a substance that reduces the surface tension of the fluid lining the alveoli, preventing them from collapsing during exhalation.
  • 3Not being able to explain the countercurrent flow mechanism in fish gills. Water flows over the gill lamellae in the opposite direction to the blood flow in the capillaries, which maintains a steep concentration gradient for oxygen diffusion along the entire length of the lamella.

Gas Exchange exam questions

Exam-style questions for Gas Exchange with mark-scheme style solutions and timing practice. Aligned to AQA, Edexcel and OCR specifications.

Gas Exchange exam questions

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Practice QuestionQ1
2 marks

A student is working through a Gas Exchange problem. Solve the following and show your full working.

A) 12x + 4
B) 4(3x + 1)
C) 12x − 4
D) 3x + 4

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Step-by-step method

Step-by-step explanation

4 steps · Worked method for Gas Exchange

1

Core concept

Gas exchange is the physical process by which gases move passively by diffusion across a surface. In A-Level Biology, this focuses on the exchange of oxygen and carbon dioxide between an organism and …

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2

Worked method

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Frequently asked questions

  • How is the structure of the alveoli adapted for gas exchange?

    Alveoli have a very large total surface area, a wall that is only one cell thick, and a rich network of capillaries, all of which maximise the rate of diffusion of oxygen into the blood and carbon dioxide out of the blood.

  • What is the Bohr effect?

    The Bohr effect is the phenomenon where an increase in carbon dioxide concentration in the blood leads to a decrease in the affinity of haemoglobin for oxygen. This results in more oxygen being released to respiring tissues where CO2 levels are high.

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